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| Artikel-Nr.: 5667A-9783319499673 Herst.-Nr.: 9783319499673 EAN/GTIN: 9783319499673 |
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| This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. The contributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The book covers the identification of LRRK2 as a major contributor to the pathogenesis of Parkinson's Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration. Weitere Informationen: | | Author: | Hardy J. Rideout | Verlag: | Springer International Publishing | Sprache: | eng |
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| Weitere Suchbegriffe: GTPase, Parkinson's Disease, kinase, neurodegeneration, signaling, Neuro..., Neurologie / Neuro..., Neurologie, GTPase; Parkinson'sDisease; neurodegeneration; Signaling |
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